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Objectives: Define cannabis components; map the anatomical distribution of the Endocannabinoid
System (ECS); evaluate Cytochrome P450 (CYP450) metabolic pathways.

Content Outline: Phytocannabinoids (THC, CBD, CBG, CBN) vs. endogenous ligands (Anandamide, 2-
AG). Functional mechanics of $CB_1$ and $CB_2$ receptors. Hepatic clearance profiles and high-risk
drug interactions (e.g., Warfarin, Clobazam).

Activities: High-definition schematic video lectures; guided independent analysis of peer-reviewed
pharmacokinetic data.

Course Content

Module 1: Lesson 1
Module 1: Lesson 2
Question 1.1: Drug-Drug Interactions (Anticoagulation)
Question 1.2: Receptor Pharmacodynamics (THC vs. CBD)